ATTAIN-2 (NCT05872620) was a Phase 3, 72-week, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of various doses of orforglipron with placebo in adults with obesity or overweight and type 2 diabetes
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"If any of the Chinese manufacturers launch an oral drug at Rs500 to Rs800 per month, it doesn't just undercut local brands
Other reported effects Beyond GI symptoms, clinical trial data reported several other effects worth noting for research protocol design
Sepsis often leads to neurological complications such as delirium and sepsis-associated encephalopathy (SAE), which are linked to increased mortality, prolonged intensive care unit stays, and persistent cognitive impairments (49)
AP39 also exhibited antioxidant effects by reducing ROS and MDA levels, increasing GSH levels, and superoxide dismutase (SOD) activity