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doi: 10.1186/s12967-018-1427-5

Low blood levels of the vitamin have been linked to several health problems

Nutrient Deficiencies Affecting Cochlear and Neural Function Cochlear hair cells are among the most metabolically demanding cells in the body, relying on adequate nutrient supply to maintain their electrochemical function and repair capacity

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Neelakantan and colleagues (Biochem Pharmacol, 2018) reported that 1-methylquinolinium and 1-methylnicotinamide showed no measurable passive diffusion in their assays, whereas 5-amino-1MQ crossed by both passive and active routes with no detectable efflux in Caco-2 cells, and lowered intracellular 1-methylnicotinamide in differentiated 3T3-L1 adipocytes with an EC near 2.3 M

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