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For a recent phase 2 trial, French researchers gave 156 people in the early stages of Parkinsons a GLP-1 agonist (lixisenatide) or placebo every day for 1 year

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A study in the Biochemical Journal showed that mice given IGF-1 LR3 experienced a 2.5x degree of anabolic muscle-building effects compared to mice receiving stand-alone IGF-1: The administration of insulin-like growth factor-I (IGF-I) via subcutaneously implanted osmotic pumps partially reversed a catabolic state produced by the co-administration of 20 micrograms of dexamethasone/day to 150 g male rats

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But the scientists discovered that these rats are also very sensitive to GLP-1 drugs, which drastically reduced their water consumption