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The diagnostic criteria for IC/BPS, based on the proposed guidelines of the European Society for the Study of Interstitial Cystitis, constituted chronic pelvic pain, pressure, or discomfort perceived to be related to the urinary bladder accompanied by at least one other urinary symptom, such as persistent urge to void or urinary frequency, for more than 6 months, and the exclusion of potentially similar diseases 11,25

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Systemic Anti-Inflammatory Effects Patients with chronic inflammation, autoimmune conditions, or systemic pain syndromes have shown interest in the potential anti-inflammatory properties of both peptides Clinical Perspective: While patient motivations are valid, it is essential that expectations are calibrated to current evidence