As guide- Melasma: at 4 weeks if you are lucky enough, at 2 weeks if combined with lasers, peels & medical management
Over-mixing creates an amalgam which is hard to form and porous and prone to fracture while under-mixing may create an amalgam which is too soft with too much free mercury
The direct tri-lodothyronine mitochondrial pathway: science or mythology
How to verify what you actually have Open the vial and check the label against this short checklist: If a product is labeled "bac water" but the label is missing the "0.9% benzyl alcohol" line, the contents are not USP-spec bacteriostatic water regardless of what the marketing says

Ingredients: Water, Butylene Glycol, Caprylic/Capric Triglyceride, Beeswax, Niacinamide, Cetearyl Alcohol, Isononyl Isononanoate, Arachidyl Alcohol, 1,2-Hexanediol, Polyglyceryl-3 Methylglucose Distearate, Behenyl Alcohol, Glyceryl Stearate, Betaine, Dimethyl-trimethylsilyloxysilane, Arachidyl Glucoside, Cetearyl Olivate, Arginine, Carbomer, Sorbitan Olivate, Allantoin, Glycerin, Panthenol, Tocopherol, Xanthan Gum, Glutathione(600 ppm), Dipotassium Glycyrrhizate, Ethylhexylglycerin, Disodium EDTA, Sodium Hyaluronate , Glucose, Alcohol, Malva Sylvestris (Mallow) Extract, Melissa Officinalis Leaf Extract, Alchemilla Vulgaris Extract, Achillea Millefolium Extract, Veronica Officinalis Extract, Mentha Piperita (Peppermint) Leaf Extract, Primula Veris Extract, Lycopodium Clavatum Extract, Equisetum Arvense Extract, Ceramide NP, Hydrogenated Lecithin, Polyglyceryl-10 Stearate, Sodium Hydroxide, Sodium Ascorbyl Phosphate, Biotin, Folic Acid, Pyridoxine, Cyanocobalamin, Linoleic Acid, Riboflavin, Beta-Carotene, Thiamine HCl, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Fragrance

Take 1 pouch daily* Best taken on an empty stomach at least 20 minutes before food