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The cream may be harmful if used excessively as our body already produces enough of Glutathione to carry out the functions

* Correspondence: Zhiyuan Gao, [email protected] Tian, [email protected] Gao, [email protected] These authors have contributed equally to this work ORCID: Biao Gao, orcid.org/0000-0002-8871-1733 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Reasons for fatigue Fatigue stems from physical or mental factors, including things like: Metabolic conditions such as diabetes, kidney disease, Cushing syndrome, and thyroid conditions Mental health issues such as depression, stress, eating disorders, anxiety, and burnout Cardiovascular conditions affecting blood flow, such as arrhythmias, heart disease, and heart failure Medications such as antidepressants, antihistamines, steroids, statins, and sedatives Sleep problems due to insomnia, narcolepsy, jet lag, and sleep apnea Chemical imbalances due to too little or too much of various essential nutrients, vitamins, and minerals Facts about B12 deficiency Also referred to as cobalamin deficiency and named after the scientific term for this water-soluble nutrient, a B12 deficiency can result from low dietary intake or from your body not absorbing the vitamin properly

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3) Injections or pills

B12 Deficiency Risk with HCG DIET Hormone administration and a 500 calorie diet are the hallmarks of the HCG diet