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Furthermore, repeated high-dose injections may alter the balance of antioxidants in the body, potentially triggering oxidative stress rather than reducing it

Amifostine (Ethyol): pharmacokinetic and pharmacodynamic effects in vivo

According to Google search data, about 3,000 people per month are asking this question, so its clearly a significant concern

The enhancement of Nrf2 transcription with sulforaphane or melatonin could benefit patients with LONG COVID (Post-Acute Sequelae of SARS-CoV-2 or Post-COVID-Syndrome), a significant proportion (approximately 40%) of individuals with COVID-19 experiencing a variety of symptoms (loss of smell and/or taste, fatigue, cough, aching pain, brain fog, insomnia, shortness of breath, and tachycardia) after 12 weeks (Jarrott et al., 2022

Once reconstituted, refrigerate or freeze at -4F for extended storage

Don't overthink this part too much, but first is generally best