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Aug 2024;63(5):1513-1528
[66] As of 2015, intravenously administered ALA is unapproved anywhere in the world except Germany for diabetic neuropathy, but has been proven reasonably safe and effective
But that might all change very soon
a low ratio decreases IL-12 secretion which favors a Th2 response pattern over Th1 (a condition typically associated with chronic inflammation), while an elevated ratio favors a Th1 response (Brundu et al., 2016
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