Glutathione and glutathione-related enzymes in reproduction
Dosing instructions, side effect information, and dietary guidance provided
*Correspondence: Lang Li, [email protected] These authors have contributed equally to this work This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Future generations of incretin agonists may be able to maintain the reduction in blood glucose and body weight while minimizing these off-target effects
Forms of administration and relevance to fertility support: Subcutaneous injection is common in research and allows local delivery near pelvic structures or systemic exposure
The longest rodent toxicology study (90 days) found no organ damage, hepatotoxicity, or nephrotoxicity at doses up to 50mg/kg daily, establishing a NOAEL well above human trial doses