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Whether and how any of this translates into a meaningful outcome for a specific individual is exactly the kind of question that belongs in a clinical evaluation, not a generalized article

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Instruct patients to inform their doctor that they are taking JANUMET prior to any surgical or radiological procedure, as temporary discontinuation may be required [see Warnings and Precautions (5.1)]

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Research suggests around 27% of people on Saxenda stop taking the medication due to adverse effects compared to 8-12% on Mounjaro and Wegovy

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More recent findings confirm these effects, although effect sizes are typically small and the evidence base remains heterogeneous [96]

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