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Stress Emotional stress can worsen or trigger hives, likely through cortisol and mast cell activation
However, the exact biological link remains to be confirmed in future studies
Indications Semaglutide is a prescription GLP-1 receptor agonist indicated: As an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with a body mass index (BMI) 30 kg/m (obesity), or 27 kg/m (overweight) in the presence of at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes, or dyslipidemia)
This reflects a Q4 2026 to Q1 2027 NDA submission plus the standard 12-month FDA review
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