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Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione [PMID: 12738715] Laboratory literature summary: Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies
Biological half-life Biological half-life ( elimination half-life , pharmacological half-life ) is the time taken for the concentration of a biological substance, such as a medication, to decrease from its maximum initial concentration (C max ) to the half of C max in the blood plasma
Academic Press, 231-266, 1992
Their cellular membranes sustain heavier structural hits
Treatment duration varies based on the condition being treated
Oral is most defensible when the interest is gut lining support, since that is where much of the preclinical research focused and where the oral route delivers directly
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