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Some people taking GLP-1 drugs report behavior or personality changes
A 2025 review in Mayo Clinic Proceedings reports that 40% to 70% of patients on these medications experience gastrointestinal side effects, and that first-line management is dietary: smaller and more frequent meals, adequate hydration, and steering clear of high-fat and high-sugar foods
Indeed some reports suggest that the GSTM1 genetic polymorphism may affect AFB 1 detoxification in human liver
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