switching from semaglutide to liraglutide Dose-equivalence reference based on pivotal GLP-1/dual-agonist trials: SURMOUNT-1 (tirzepatide/Zepbound, 72 weeks) STEP-1 (subcutaneous semaglutide/Wegovy, 68 weeks) OASIS-4 (oral semaglutide/Wegovy, 64 weeks). For educational comparison only—these are Effects of Switching from Liraglutide

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doi:10.1056/NEJMoa2032183 Marso SP, Bain SC, Consoli A, et al

Wendisch, [email protected] This article was submitted to Industrial Biotechnology, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Mechanism of intranasal drug delivery directly to the brain

Insert the needle straight in at a 90-degree angle, then press the injection button firmly and hold it for 3 seconds to ensure the full dose delivers