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Alterations in the normal function of excitatory amino acid carrier 1 affect cysteine transport and GSH synthesis impairing zinc homeostasis (the thiol group of GSH can function as a principal Zn 2+ chelator for the maintenance of Zn 2+ homeostasis in neurons) and oxidative stress, enhancing susceptibility to ischemia-induced neuronal cell death in the hippocampus (162164)
Additionally, factors like adherence to the prescribed dosage, potential side effects, and overall health conditions should be taken into consideration when determining the expected weight loss
Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway
Non-etheless, the effect of L-carnitine on protein synthesis seems to be the primary mechanism for protection against lenvatinib-induced muscle toxicity
We addressed the rapid clearance of this transient hepatic lipid accumulation that could be due to the strong and acute activation of lipid export, manifested by the rise of plasma TGs that transiently peaked at 24 h post-injection
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