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While riboflavin may not be a panacea for everyone with migraines, it is inexpensive, non-toxic, safe, and effective for some migraine sufferers

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doi: 10.1016/j.chom.2023.05.022 288 ZhuJ.-H.BoH.-H.LiuB.-P.JiaC.-X

Indeed, early presence of hypermethylated TSGs does not necessarily indicate an invasive cancer, as premalignant or cancer precursor lesions can also carry these epigenetic signatures