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However, during clinical trials, researchers found that it also had a significant effect on weight loss
GLP-1s have already revolutionized type 2 diabetes and obesity treatment
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2.2 Substrate-specific metabolic overload (02 h post-meal) Excess glucose engages canonical insulin signaling [insulin receptor substrate (IRS)phosphoinositide 3-kinase (PI3K)protein kinase B (Akt)] to drive glucose transporter type 4 (GLUT4) translocation in skeletal muscle and adipose tissue
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pAAV-hSyn-DIO-ChrimsonR-mRuby2-ST, plasmid from Addgene, 105448, RRID: Addgene_105448-AAV9, virus packaged at UNC Vector Core (100 l at titre 1 10 13 vg ml 1 )
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