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A 2018 review article comparing GLP-1 receptor agonists reported that, in studies, semaglutide 1 mg once weekly resulted in a mean weight loss from 4.53 to 6.5 kg, while dulaglutide at 1.5 mg once weekly resulted in a mean weight loss from 0.87 to 3.03 kg
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SURMOUNT-1 and SURMOUNT-2 showed cholelithiasis in 1.1% of tirzepatide-treated patients versus 1.0% on placebo
