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Modis, K., Ju, Y., Ahmad, A., Untereiner, A
Although NRF2 does not directly regulate serine synthesizing enzyme genes, ATF4, a key regulator of serine synthesis, was shown to be activated by NRF2
Ultimately, identifying the autoantigenic targets of FM IgG will increase specificity to differentiate between FM patients with and without autoantibodies and between other pain conditions and HC subjects who have nonpathogenic anti-SGC IgG
This dual action is thought to account for its observed cytoprotective effects in gastrointestinal and hepatic injury models
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