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So I think what changed is normally this response is, like, seconds

Here are some general recommendations: Dietary Guidelines Focus on nutrient-dense foods, such as lean proteins, whole grains, fruits, and vegetables

If re-titrating from 2.5 mg, expect 5 to 6 months to maximum dose

As a result, many patients now remain on GLP-1 therapies far beyond the timelines traditionally studied in clinical trials