Furthermore, responses of two potato cultivars (Igor and Nadine) were compared to two Potato virus Y (PVY) strains, the aggressive PVY NTN and the mild PVY N (Kogovsek et al., 2010)
In vivo, the effect is smaller and harder to measure, but skin biopsy studies in trials have shown modest collagen density improvements after weeks of topical use
The results in mouse models were impressive
Panczenko-Kresowska B, Ziemlaski S, Rudnicki S, Wojtulewicz L, Przepirka M
Spatial transcriptomics combined with single-cell RNA sequencing identified high expression levels of ferroptosis-related genes, including TFRC, NCO4, and SLC3A2, in granulosa cells of patients with ovarian senescence, while GPX4 expression was notably low (Lin et al., 2023)
TGF- also enhances glycolysis, increasing the generation of 3-phosphoglycerate (3-PG), a critical intermediate that feeds into serineglycine metabolism [108, 109]