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Animal models, predominantly rat Achilles tendon studies, demonstrate that BPC-157 significantly shortens healing time relative to untreated controls, with histological analysis showing improved collagen fiber organization at the injury site
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In the U.S., concentrations of 4% or higher are available as a prescription or compounded to treat stubborn pigment conditions like melasma, says Dr
For the primary composite outcome and secondary hierarchical outcomes, the threshold for two-sided statistical significance was set to 0.0322 (one-sided level 0.00161) using Lan-DeMets alpha spending function, which allows to adjust significance levels as data were reviewed for the interim analysis, reducing the chance of false positive results
Note that supplemental magnesium has an upper safe limit (typically 400mg/day for adults) and higher doses can cause diarrhoea