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Collectively, these findings underscore a pathogenic synergy wherein -syn aggregation and lipid peroxidation co-amplify each other, culminating in ferroptotic cell death and neurotoxicity

The cellular protein Tip60 (Tat-interacting protein), initially identified as an interactor of HIV-1 Tat, has emerged as a significant research focus due to its involvement in diverse cellular processes, including chromatin remodeling, DNA damage response and repair, cell cycle arrest, and apoptosis 79

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