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This highlights that the GLP-1 therapy should go hand in hand with dietary adjustments and exercise

Over-the-counter antidiarrheal medications like loperamide can be used judiciously for diarrhea (avoiding use if fever, blood in stool, or infection is suspected), though patients should consult their healthcare provider before regular use

Endocrinology 153 , 58665874 (2012)

Why are so many people experiencing benefit from the GLP-1 analogs

GLP-1 RAs augment insulin secretion after meals and inhibit glucagon production from pancreatic alpha cells at hyper- or euglycemia

Mechanism of Action Tirzepatide: Dual-agonistit targets GLP-1 and GIP receptors