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The pharmacokinetics, dose-response, safety, and outcomes data for this use are minimal in published literature
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Overlap of the R152H variant backbone with wild-type was performed in the panel on the right, where the major conformational change in the loop around His152 was colored (WT as in pale pink and R152H as in red)
Some exploratory findings favoured early treatment, but the principal between-group infarct-area comparison did not reach statistical significance.[17] TB-500 generally refers to a synthetic fragment associated with the LKKTETQ sequence
Kahroba H, Ramezani B, Maadi H et al (2021) The role of Nrf2 in neural stem/progenitors cells: from maintaining stemness and self-renewal to promoting differentiation capability and facilitating therapeutic application in neurodegenerative disease
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