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LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells
J Plant Chemist Ecophysiol 1:1009 Verma N, Singh AP, Gupta A, Sahu PK, Rao CV (2011) Antidiarrheal potential of standardized extract of Rhododendron arboreum Smith flowers in experimental animals
That matters because repeated injections in the same spot can cause lipohypertrophy, a thickened or lumpy area under the skin that may alter absorption
Tortora F, Notariale R, Lang F, Manna C
257,258 The Hippo pathway also modulates apoptosis, as MST1/2 signaling can activate proapoptotic programs, whereas oncogenic RAS, PI3K/AKT, and RAF signaling suppress MST2 activity and promote cancer cell survival
Its core mechanism is actin sequestration: it binds G-actin monomers, blocking polymerisation, which is exactly the condition cells need to migrate, contract wounds, and build new vessels
