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References Anemia, Pernicious- Rare Disease Database, NORD, National Organization for Rare Disorders [Internet]

For IM injections, a 22 to 25 gauge needle is typically used

Keep reconstituted vials refrigerated

The STEP 5 trial demonstrated that continued treatment for 104 weeks maintained weight loss, while the STEP 1 extension study showed that discontinuing semaglutide at 68 weeks led to two-thirds of the weight lost being regained within a year

Figure 1: Changes in gross morphological scores amongst the four experimental treatment groups

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