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Gastrointestinal Effects The most commonly reported adverse effects are gastrointestinal in nature, including: Nausea and vomiting (affecting 20-40% of patients initially, varying by agent and dose) [8] Diarrhoea or constipation Abdominal discomfort and bloating Reduced appetite In elderly patients, persistent nausea and vomiting can lead to dehydration and electrolyte imbalances more rapidly than in younger adults

S., Smith, L

Inadequate hormone levels can lead to: Weight gain Loss of lean muscle mass Low energy Poor sleep Mood disturbances Decreased libido Decreased bone density Hormone therapy can replace or optimize your hormones to help you reach your health goals

In general, prescriptive skincare ingredients are better than oral supplements including polypodium & glutathione

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Diet In addition to or instead of supplementation, you can amplify astaxanthins effects (or support similar pathways) through diet