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6.10.5 Drugs 6.10.5.1 Rosiglitazone Rosiglitazone, a PPAR- agonist, may alleviate ovarian fibrosis by suppressing the transduction of TGF-1 and lowering CTGF levels in a rat model of PCOS (282)
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Improved metabolic health can also lead to better energy levels, mood, and overall well-being
n=4 per group)
Results: Alcohol binges in a diet-induced model of NASH lead to increased liver injury (transaminases level), profound fibrosis [protein level alpha-smooth muscle actin (-SMA) and vimentin], neutrophil infiltration (Ly6G + ) and NETs formation (neutrophil elastase and citrullinated histone) compared to lean and NASH alone mice
