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CBN.com - The Christian Broadcasting Network

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Under conditions of chronic energy flux constriction, compartment-specific regeneration efficiency may therefore become more relevant than bulk metabolite concentration

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2.4 Data synthesis The available data from the included studies and their supplementary files were presented comprehensively to synthesize the existing evidence from the selected eligible systematic reviews and meta-analyses

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A major mechanism involves the reduction of intracellular drug accumulation through downregulation of solute carrier (SLC) transporters or upregulation of ATP-binding cassette (ABC) transporters, resulting in decreased drug efficacy

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