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2010;5(3):e9590

The following best practices reflect standard pharmaceutical research guidance for lyophilised peptide compounds, as set out in the MHRA GCP Guide, EU GMP Annex 13 (Investigational Medicinal Products), and EU/UK GDP guidelines

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[57] Preclinical studies suggest semaglutide counteracts these processes by activating the AMPK and SIRT1 pathways, which are fundamental for cellular autophagy and mitophagy