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Virani SS, Newby LK, Arnold SV, et al
50 & Target [1] In Vitro Promazine hydrochloride shows K D s of 25, 190 and 8400 nM at the human norepinephrine transporter, serotonin transporter, and dopamine transporter, respectively [3]
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Higher-frequency or higher-volume experimental protocols may increase the likelihood of sensitivity-related observations or tolerability concerns
In addition, one exploratory cohort that enroled 13 participants was used to evaluate digital tools and two open-label cohorts enroled 14 participants to evaluate dose-escalation strategies
