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Most available evidence comes from the broader class of GLP-1 receptor agonists rather than tirzepatide specifically
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Similar studies of Lillys drugs have shown there may be risks to the fetus from exposure during pregnancy, the company said
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It is important to emphasise several key points: Evidence relates to semaglutide at weight management doses (2.4 mg) , not specifically to Ozempic at diabetes treatment doses Studies have focused on osteoarthritis , not rheumatoid arthritis or other inflammatory arthropathies Long-term data on joint outcomes remain limited Individual responses vary considerably For rheumatoid arthritis and other inflammatory forms of arthritis, there is insufficient evidence to suggest that Ozempic or weight loss alone would adequately control disease activity
Powder is more stable, but moisture absorption or clumping is a sign of structural change and possible contamination
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