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doi: 10.1016/j.foodchem.2020.127833 115
COAs are not published publicly to protect supply-chain privacy and prevent competitor scraping
The bridge from genes changed to cell function changed is still half-built, and most of the published work leans on dermal fibroblasts, with far less on the cardiac, lung, or joint varieties, which makes generalizing across tissue types shakier than it sounds
The choice usually depends on tolerance, convenience, regulatory access, and cost not a clear human-efficacy ranking
Notably, endogenous GHK-Cu levels in human plasma are age-dependent, dropping from ~200 ng/mL at age 20 to below 80 ng/mL after age 60
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