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Graphical abstract Similar content being viewed by others Introduction Cardiovascular disease (CVD) is the predominant cause of death worldwide, with a substantial proportion attributable to ischemic heart disease, caused by atherosclerotic coronary artery disease (CAD) (Glovaci et al

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N Engl J Med 355:22972307 Aithal GP, Thomas JA, Kaye PV et al (2008) Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis

Role of fat and adipokines in intestinal inflammation

Because they might

For the general population without these risk factors, the theoretical concern remains speculative