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Unfortunately, glutathione levels decrease with age, stress, lack of proper diet, exposure to toxins, and diseases such as diabetes
In addition, SLC7A11, the antiporter providing intracellular cystine (necessary to maintain intracellular GSH levels) also increased (Figure 2C and Supplemental Figure 2A)
Huanglian Jiedutang is a classical formulation used to clear heat and purge fire
Collectively, these metabolites reinforce enzymatic defenses and enhance cellular resilience under abiotic stress