For example, the structure of the ECM sequesters antifungal agents and slows down the diffusion of the antifungal agent to the cells of the biofilm, the efflux pumps and stress response systems in the biofilm cells are markedly upregulated
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Results and discussion Optimization of separation and analytical conditions Selection of stationary and mobile phase Preliminary screening of stationary phases (Table S2) in combination with various mobile phase additives (e.g., FA, ammonium formate/bicarbonate, TFA, DFA) was conducted for the separation of GSH and gGC
The effects vary according to the type of target cell, the G proteins and kinases involved, and the phosphorylation of proteins
This is achieved by transporting glutamate to the mitochondrial matrix through a mitochondrial aspartate/glutamate carrier aralar [91, 92]
Wrap the ice pack in a cloth or towel to prevent freezing damage