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Lee et al., 2016

Accordingly, and in line with currently ongoing trials in HFpEF (ClinicalTrials.gov IDs NCT04916470 and NCT04788511), it may be relevant to consider obesity-related HFpEF as a specific (sub)phenotype, whether coexisting with type 2 diabetes or not

172 Alpha-glycerylphosphorylcholine (-GCP) is another source of choline and therefore a possible precursor of phosphatidylcholine and acetylcholine

Patients initiating GLP-1 RA treatment (semaglutide, liraglutide, tirzepatide) were propensity scorematched (1:1) with RA controls not receiving GLP-1 RA therapy, balancing demographics, BMI categories, cardiovascular comorbidities, immunosuppressive therapies, and cardiometabolic medications

It took he and his team nine years to achieve the goal

In particular, exendin-4 was discovered in the secretions of the venom glands of the Arizona gila monster (Heloderma suspectum), which actively interacts with human GLP-1 receptors while being resistant to the action of DPP-4 The effects of GPP-1, GIP, and their inactivation by the enzyme DPP-4, leading to short-term action, are described above