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Similarly, nanostructured lipid carriers provide a stable matrix that simultaneously accommodates lipophilic and hydrophilic polyphenols, enhancing their sustained release and biological action within the brain [269]

Again, the loss of correlations in the pathway metabolite may be lost in patients due to illness-related, and also perhaps treatment influences, on 5-HIAA, since the TRP5-HIAA correlation is appears weakened in patients (Yao et al., 2010a)

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