in Comprehensive Insect Physiology, Biochemistry and Pharmacology (eds Kerkut, G
The time it takes for vitamin B12 (cobalamin) treatment to produce noticeable effects varies considerably depending on the severity of deficiency, the route of administration, and individual patient factors
Red blood cell breakdown (also known as hemolysis) in G6PD deficiency can manifest in many ways, including the following: Prolonged neonatal jaundice, possibly leading to kernicterus (arguably the most serious complication of G6PD deficiency) Hemolytic crises in response to: Illness (especially infections) Certain drugs (see below) Certain foods, most notably broad beans, from which the word favism derives Certain chemicals Diabetic ketoacidosis Hemoglobinuria (red or brown urine) Very severe crisis can cause acute kidney injury Favism is a hemolytic response to the consumption of fava beans, also known as broad beans
Winkler, B
Schwarz, K
When this ratio collapses, the cell enters a state of severe oxidative stress, leading to accelerated aging, mitochondrial dysfunction, and eventually, cellular death (apoptosis)