Acknowledgements This work was supported by the National Key Research and Development Program of China (2021YFF1000601), the National Natural Science Foundation of China (32172700) and the Joint Funds of the National Natural Science Foundation of China (U20A2052), and the Fundamental Research Funds for the Central Universities (grant number 2662018PY043)
These damaged T-cells produce markedly less protective cytokines like IFN- and TNF- when stimulated, leaving the patient vulnerable to opportunistic infections and viral reactivation
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