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Since intense nausea can absolutely drain your energy, this indirect effect might mean Tirzepatide feels 'smoother' for certain individuals
However, many endocrinologists have called the overall efficacy transformative
Contrave works on brain chemistry instead, produces a more modest 5 to 8 percent average, but comes without the GI side effects, injection requirement, or cost barriers that keep some patients away from GLP-1s
Patients were identified through electronic medical records and used propensity score matching to compare them with a similar cohort of more than 385,000 patients who had never received GLP-1-RA therapy and did not have a prior AFib diagnosis
Epub 2004 Oct 7
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