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Between the two, semaglutide and tirzepatide consistently lead the clinical data, and the right choice usually depends on BMI, metabolic history, and how the body responds to the starting dose

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Always consult with a healthcare professional before starting any new supplement regimen

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Those who respond well to split dosing often cite faster initial improvement and more stable progress throughout the treatment period

Other concerns flagged included suspicions around the timeline between attaining ethical approval and actually commencing the study, the fact that the trial was not randomized considered by many to be the gold standard for clinical trials and the removal of four treated patients from the final dataset, three of whom were escalated to intensive care and one of whom died