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GLP-1 signalling remains largely intact in obesity and type-2 diabetes, while GIP signalling appears blunted, a finding that, paradoxically, did not deter Eli Lilly from pursuing GIP agonism in tirzepatide
Khera R, Angraal S, Couch T, Welsh JW, Nallamothu BK, Girotra S, Chan PS, Krumholz HM
As healthcare professionals, we owe it to our patients to move past K52.9
For example, a study published in the Journal of Nutrition found that supplementation with N-acetylcysteine (a precursor to glutathione) eliminated negative effects of oxidative stress, even when they were exposed to high levels of oxidative stress
Reports have emerged of adverse effects such as nausea, gastrointestinal discomfort, and unexpected blood sugar changes
