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PARP Enzyme Substrate Poly(ADP-ribose) polymerases (PARPs) consume NAD+ as a substrate during DNA damage repair, using it to synthesize poly(ADP-ribose) chains that recruit DNA repair machinery to sites of strand breaks
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The researchers note that pricing structures may play a role, as lower doses are sometimes offered at reduced prices through self-pay channels
A team from Tehran University of Medical Sciences and Shahid Beheshti University of Medical Sciences in Tehran, Iran, did compile the results of these trials in a systematic review and meta-analysis that was described in a publication in Frontiers in Nutrition in October 2022
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