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SL derived from Bacteroides can be incorporated into host lipid metabolic pathways and function as signaling molecules, interacting with host receptors such as Toll-like receptor 2 to influence macrophage activation and cytokine production

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Unlike other compounds that act through vascular pathways, PT141 acts directly on the central nervous system , making it a unique agent in neurobehavioral and sexual health research

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1 Introduction Obstructive sleep apnea syndrome (OSAS) is a chronic sleep-related breathing disorder characterized by recurrent upper airway collapse during sleep, leading to intermittent hypoxemia, sleep architecture disruption, and impaired daytime functioning (1, 2)