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Kilic M, Keskek M, Ertan T, Yoldas O, Bilgin A, Koc M
It was clinically approved by both the Food and Drug Administration (FDA) and the European Medicine Agency (EMA) in 2014 for the treatment of relapsing-remitting multiple sclerosis (MS), showing a significant efficacy over 2 years versus placebo and a favorable benefit-risk profile in two phase-III clinical trials, although with several adverse effects such as nausea, diarrhea, abdominal pain and leukopenia in some patients [282, 283]
Shang, L., Dong, S
Since its discovery by researchers at the University of Zagreb in 1993, this peptide has demonstrated remarkable healing properties across numerous preclinical studies
It could also be due to the adipocyte dysfunction linked to low vitamin B12 levels through cellular inflammation
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