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4 and Extended Data Table 3)
Some studies suggest menstrual regularity and ovulation may improve, especially when weight loss and insulin sensitivity improve
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas
The pharmacokinetic parameters included area under the curve plasma concentrations (AUC), maximal plasma concentration (C max ), time to C max , half-life (t 1/2 ), and clearance
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