Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies
The authors declare no competing interests
J Pulm Respir Med
Over time, the nervous system may become more sensitive, so attacks become longer, more frequent, or are replaced by constant burning pain
Metabolites generated from MG integrate into central carbon metabolism, facilitating metabolic reprogramming during stress
Astrocytes are highly responsive glial cells that interact with immune and neural cells and become activated when encountered with any foreign insult, including chronic injuries, infections, acute trauma and neurodegenerative diseases 20