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According to the MHRA-approved product information, these include: Nausea (very common, affecting more than 1 in 10 patients) Vomiting and diarrhoea (common, affecting up to 1 in 10 patients) Abdominal pain and constipation (common) Decreased appetite (common) These gastrointestinal symptoms typically occur during the initial weeks of treatment or following dose escalation and often diminish over time as the body adjusts to the medication

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Some participants in GLP-1 weight loss programs have experienced more severe side effects, though they are less common

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In most cases, shedding decreases once caloric intake stabilizes and metabolic stress declines

Laboratory research record on GLP-1S [PMID: 33439580] PubMed laboratory record discussing GLP-1S in a research context